100% FRUITING BODY EXTRACT
GLUTEN-FREE
ORGANIC
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COMPREHENSIVE NERVOUS SYSTEM SUPPORT
The nervous system provides an interface between us and the environment, taking in sensory information, integrating it, processing experience, and allowing us to move in and through the outside world. It also gives us the capacity to think, feel, and remember, and to have an experience of life as we live it. Such complex functions have requirements that we often take for granted: efficient propagation of membrane potentials, maintenance of stable intracellular environments, a constant need for neuronal remodeling and repair, and the ability to adapt to changing metabolic conditions.
Lucidum Medicinals has formulated Brain and Nerves with well-researched mushrooms to support a healthy memory, mood, optimal nerve and brain function, and a healthy stress response.*
Background
The nervous system is composed of a collection of neurons and specialized support cells that facilitate communication throughout the body - not unlike an internal mycelial network. There are many potential causes of nervous system impairment, including genetic factors, prolonged inflammation, poor sugar metabolism, physical nerve damage, and a suboptimal microbiome. These factors alone or in combination with each other influence the nervous system's susceptibility to long term damage.
Mushrooms support the nervous system through many mechanisms, supporting a healthy response to inflammation, healthy glucose metabolism, neuronal repair and neurogenesis, and promoting a healthy intestinal microbiome.
LION'S MANE
Lion's mane mushroom is well known for memory support. Multiple clinical trials demonstrate lion's mane’s ability to significantly improve subjective memory in adults. Animal trials suggest that lion's mane also speeds recovery time after damage to peripheral nerves, and additional research shows improvements in the gut microbiome and a healthy inflammatory response following ingestion.
Action | Mechanism |
|---|---|
Glucose-regulating | Unknown |
Prebiotic | Digestion of polysaccharides by beneficial microbiota |
Inflammation modulating | Modulates inflammatory cytokines |
Neuroinflammation modulating | Diminishes glial cell activation |
Neurotrophic | Stimulates nerve growth factor synthase (NGFS) |
Nootropic; neuroprotective | Stimulates nerve growth factor synthase (NGFS); inhibits plaque growth; promotes hippocampal neurogenesis |
Oyster mushroom is best known as a delicious food, and is rich in the amino acid ergothioneine. Ergothioneine easily crosses the blood brain barrier, supports a healthy response to oxidative damage, and promotes a healthy memory.
OYSTER MUSHROOM
Action | Mechanism |
|---|---|
Neuroprotective, antioxidant | Reduces neuronal oxidative stress |
Inflammation modulating (topically) | β-glucan-induced modulation of inflammation |
Immune modulating | Increases NK cells; reduces frequency of respiratory infections
|
Anti-allergic | Modulates IgE production; reduces eosinophilia
|
Anti-atherogenic | Diminished lipid peroxidation; inhibits HMG-CoA reductase; inhibits angiotensin-converting enzyme (ACE) |
Tremella is made up of almost 90% polysaccharides, compared to a more typical 30% in many mushrooms. These polysaccharides act as prebiotics for gut bacteria, promoting a healthy gut microbiome. In a randomized controlled trial, tremella demonstrated efficacy in supporting a healthy memory, executive function, and increased subjects’ gray matter brain volume.
TREMELLA
Action | Mechanism |
|---|---|
Prebiotic | Digestion of polysaccharides by beneficial microbiota |
Hypoglycemic | Delays gastric emptying; increases insulin secretion |
Nootropic | Increases gray matter brain volume |
